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Queen Elizabeth II has expressed her remorse over the deadly Manchester Arena blast that left 22 dead and scores injured.

In a statement released Tuesday, the monarch called the attack — which took place just as American pop star Ariana Grande was closing out the packed England show — an "act of barbarity." The queen offered her "deepest sympathy" to all the families affected by the tragedy.

The full statement can be read below:

The whole nation has been shocked by the death and injury in Manchester last night of so many people, adults and children, who had just been enjoying a concert.

I know I speak for everyone in expressing my deepest sympathy to all who have been affected by this dreadful event and especially to the families and friends of those who have died or were injured.

I want to thank all the members of the emergency services, who have responded with such professionalism and care.

And I would like to express my admiration for the way the people of Manchester have responded, with humanity and compassion, to this act of barbarity.

The Queen's grandson, Prince William, also released a statement on Tuesday paying tribute to the victims and their families who have been forced to confront "unimaginable grief."

The Queen and her husband, Prince Philip, also paused to observe a minute of silence at a Buckingham Palace garden party on Tuesday in honor of the Manchester victims.

On Tuesday morning, the Islamic State claimed responsibility for the deadly blast via the messaging app Telegram.